Fluticasone Propionate 0.05% Topical
Children, pregnancy, lactation, concomitant skin infections. Concomitant skin/lung/systemic infections. Advised to rinse mouth with water every time after inhalation. Application to large areas, broken skin or under occlusive dressings. Lactation: Excretion in milk unknown; use with caution
Psoriasis, Eczema, Corticosteroid-responsive dermatoses
Hypersensitivity. Acne vulgaris, rosacea, perioral dermatitis, skin atrophy; hypersensitivity. Primary cutaneous viral infections (e.g. herpes simplex, chicken pox), perianal and genital pruritus, primary fungal or bacterial skin infections. Inhalation: Status asthmaticus.
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1-10% Pruritus (2.9%),Dryness (1.2%),Skin irritation: (3%),Eczema (1%),Telangiectasia (2-5%),Numbness of fingers (1%) <1% Burning,Folliculitis,Acneiform lesions,Urticaria,Hypertrichosis,Lightheadedness,Viral,Warts,Impetigo,Skin infection Frequency Not Defined Striae,Pigmentation changes,HPA suppression (with higher potency used >2 wk),Erythema,Cushing syndrome,Sepsis,Hemorrhage reported,Edema/swelling Potentially Fatal: Suppression of immune system.
Fluticasone utilises a fluorocarbothioate ester linkage at the C17 position. It has potent vasoconstrictive and anti-inflammatory activity, but weak HPA inhibitory effect when applied topically.
May lead to increased plasma concentrations of fluticasone when used with CYP4503A4 inhibitors such as ritonavir.
Pregnancy Category: C Lactation: Excretion in milk unknown; use with caution
Topical cream Atopic Dermatitis, Corticosteroid-responsive Dermatoses Apply a thin film to the affected skin areas once or twice daily. Rub in gently. Reassess diagnosis if no improvements within 2 weeks
Topical cream Atopic Dermatitis, Corticosteroid-responsive Dermatoses Child > 3 months: Apply a thin film to the affected skin areas once or twice daily.
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