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Slipam - 15mg
Capsule* Delivery will be done in Dhaka city only.
More Information About - Slipam - 15mg
Description
Generic Name
Flurazepam
Precaution
Chronic pulmonary insufficiency; elderly or debilitated patients; muscle weakness, impaired liver or kidney function; drowsiness may affect skilled tasks; monitor cardio-respiratory function when used for deep sedation; personality disorders or organic brain changes; history of alcohol or drug addiction. Respiratory depression and hypotension with parenteral admin. Dependence; lactation. Safety and efficacy are not proven in children <15 yr. Lactation: Excretion in milk unknown; not recommended
Indication
Insomnia
Contra Indication
Hypersensitivity; porphyria. Pregnancy (3rd trimester); neonates.
Dose
N/A
Side Effect
Common Ataxia,Dizziness,Drowsiness,Lethargy,Light-headedness Less Common Chest pain, palpitations,Headache, irritability, nervousness, weakness,GI complaints,Myalgia,GU complaints Rare Elevations of AST, ALT, bilirubin (T&D), alk phos
Pregnancy Category
Name : X
Description
Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.Mode of Action
Flurazepam is a long-acting benzodiazepine which binds to stereospecific benzodiazepine receptors on the postsynaptic GABA neuron w/in the CNS, including the limbic system, reticular formation. It enhances the inhibitory effect of GABA on neuronal excitability by increasing neuronal membrane permeability to Cl ions, thus resulting in hyperpolarisation and stabilisation.
Interaction
May enhance CNS depressant effect w/ antidepressants, antipsychotics, general anaesth, hypnotics or sedatives, opioid analgesics. Flurazepam clearance may be reduced by cimetidine, and may be increased by rifampicin.
Pregnancy Category Note
Pregnancy Category: X Lactation: Excretion in milk unknown; not recommended Minor tranquilizers should be avoided in 1st trimester of pregnancy due to increased risk of congenital malformations Maternal use shortly before delivery is associated with floppy infant syndrome (good and consistent evidence) Prenatal benzodiazepine exposure slightly increased oral cleft risk (limited or inconsistent evidence)
Adult Dose
Oral Short-term management of insomnia Adult: 15-30 mg at night. Elderly: Max: 15 mg at night.
Child Dose
Oral Short-term management of insomnia Child: >15 yr 15 mg at night. Elderly: Max: 15 mg at night.
Renal Dose
N/A
Administration
May be taken with or without food.
Disclaimer
The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.
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