Danflex - 25mg

Capsule

Pack Size : 10 Capsule x 1 Strip

Generics : Dantrolene Sodium

Manufacturer : Opsonin Pharma Ltd.

Best Price * TK 100.00

* Delivery will be done in Dhaka city only.

Alternative Product

Capsule Relaxo - 25mg Ziska Pharmaceuticals Ltd.

Tk 10.00

Capsule Relaxo - 50mg Ziska Pharmaceuticals Ltd.

Tk 15.00

Capsule Danflex - 50mg Opsonin Pharma Ltd.

Tk 15.00

More Information About - Danflex - 25mg

Description

Generic Name

Dantrolene Sodium

Precaution

Perform LFTs before and during treatment. Increased risk of liver injury in patients >30 yr, female patients especially those on oestrogen therapy, history of liver disease or patients with daily dose >400 mg. Cardiac or pulmonary disorders. Pregnancy. Lactation: enters breast milk/not recommended

Indication

Muscle tightness, muscle cramping (spasms), muscle pain caused by spinal cord injury, stroke, cerebral palsy, multiple sclerosis.

Contra Indication

Active liver disease; acute muscle spasm; patients who use their spasticity to maintain posture or function. Lactation.

Dose

N/A

Side Effect

Fatigue, muscle weakness/pain. GI disturbances, CNS effects, tachycardia, unstable BP, dyspnoea, drowsiness, rashes, pruritus, chills and fever, visual disturbances, dysphagia, speech disturbances; haematuria, crystalluria, urinary frequency, retention and incontinence. Increased serum AST (SGOT), ALT (SGPT), alkaline phosphatase, LDH, BUN, and total serum bilirubin concentrations, Difficult erection, Abnormal hair growth, Aplastic anemia, Anemia, Leukopenia, Lymphoma, Thrombocytopenia Potentially Fatal: Hepatotoxicity, pleural effusion with pericarditis.

Pregnancy Category

Name : C

Description

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Mode of Action

Dantrolene has a direct action on skeletal muscle. It uncouples muscular contraction from excitation, probably by interfering with calcium release from sarcoplasmic reticulum.

Interaction

CNS depressants; oestrogens; calcium-channel blockers. CNS effects enhanced by alcohol or CNS depressants.

Pregnancy Category Note

Pregnancy Category: C Lactation: enters breast milk/not recommended

Adult Dose

Oral Spasticity Adult: Initially, 25 mg daily increased gradually at 7-day intervals over 7 wk. Discontinue if no response after 45 days of treatment. Max: 100 mg 4 times daily.

Child Dose

Oral Spasticity Child: Initially, 0.5 mg/kg once daily, may increase gradually to 2 mg/kg 3-4 times daily. Max: 100 mg 4 times daily.

Renal Dose

N/A

Administration

May be taken with or without food.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.