FDA has not yet classified the drug into a specified pregnancy category.
Mode of Action
Alumunium hydroxide acts on the HCl in the stomach by neutralization, forming aluminium chloride salt and water.
Magnesium hydroxide increases peristaltic activity causing osmotic retention of fluids, thus resulting in bowel evacuation. It also reduces stomach acid by reacting with hydrochloric acid to form Mg chloride.
Interaction
Aluminium Hydroxide: Enhanced absorption with citrates or ascorbic acid. Decreases absorption of allopurinol, tetracyclines, quinolones, cephalosporins, biphosphonate derivatives, corticosteroids, cyclosporin, delavirdine, Fe salts, imidazole antifungals, isoniazid, mycophenolate, penicillamine, phosphate supplements, phenytoin, phenothiazines, trientine.
Magnesium Hydroxide: Decreases absorption of tetracyclines and biphosphonates. Separate administration of these and other drugs by around 2 hr.
Pregnancy Category Note
N/A
Adult Dose
Chew 1-2 tablets after meals and at bedtime as needed (up to 4 times a day).
Do not take more than 16 tablets in 24 hours
Child Dose
N/A
Renal Dose
N/A
Administration
After meals and at bedtime as needed. For best results, drink a half glass of water or other liquid after each dose.
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