Hepatic and renal impairment; pregnancy. Efficacy has not been established in angle-closure glaucoma. Ensure an interval of at least 10 minutes between admin of different ophthalmic solutions.
Lactation: Not known if distributed in breast milk; not recommedned (discontinue drug or do not nurse)
Indication
Open-angle glaucoma , ocular hypertension
Contra Indication
Brinzolamide 1% ophthalmic suspension is contraindicated in patients who are hypersensitive to any component of this product.
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks
Mode of Action
Brinzolamide is a carbonic anhydrase inhibitor that decreases secretion of aqueous humor thus reducing intraocular pressure.
Interaction
Brinzolamide: Concurrent use w/ oral carbonic anhydrase inhibitors may lead to additive systemic effects. Concurrent use w/ high-dose salicylates may lead to toxicity.
Pregnancy Category Note
Pregnancy Category: C
Lactation: Not known if distributed in breast milk; not recommedned (discontinue drug or do not nurse)
Adult Dose
Adult: Ophth Open-angle glaucoma; Ocular HTN As 1% susp: Instill 1 drop 2-3 times/day.
Child Dose
N/A
Renal Dose
N/A
Administration
May be used concomitantly with other topical ophthalmic drug products to lower intraocular pressure; if more than one topical ophthalmic drug being used, administer at least ten min apart
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The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.