Zymarin Ophthalmic Solution 500/100 ml Eye Drops - 500 mg

Drops

Pack Size : 1 Bottle x 1 Packet

Generics : Gatifloxacin

Manufacturer : Eskayef Pharmaceuticals Ltd.

Best Price * TK 125.00

* Delivery will be done in Dhaka city only.

Alternative Product

Description

Generic Name

Gatifloxacin Eye prep

Precaution

Patients should be advised not to wear contact lenses if they have signs and symptoms of bacterial conjunctivitis. Avoid contaminating the applicator tip with material from the eye, fingers or other source.

Indication

Bacterial conjunctivitis

Contra Indication

Patients with a history of hypersensitivity to Gatifloxacin, to other quinolones, or to any of the components in this medication. Eye drops should not be injected subconjunctivally, nor should it be introduced directly into the anterior chamber of the eye.

Dose

N/A

Side Effect

1-10% Conjunctival irritation (5-10%),Incr. lacrimation (5-10%),Keratitis (5-10%),Papillary conjunctivitis (5-10%),Conjunctival hemorrhage (1-4%),Chemosis (1-4%),Dry eye (1-4%),Eye discharge (1-4%),Eye irritation (1-4%),Eye pain (1-4%),Eyelid swelling (1-4%),Red eye (1-4%),Visual acuity decr (1-4%),Taste disturbance (1-4%)

Pregnancy Category

Name : Not Classified

Description

FDA has not yet classified the drug into a specified pregnancy category.

Mode of Action

Gatifloxacin is a fluoroquinolone antibacterial which acts by inhibiting DNA synthesis in susceptible organisms via inhibition of both DNA gyrase (essential for bacterial reproduction) and topoisomerase IV (essential during bacterial cell division).

Interaction

Additive effect w/ drugs that prolong QT interval e.g. antiarrhythmic agents (amiodarone, quinidine, sotalol), arsenic trioxide, cisapride, chlorpromazine, droperidol, mefloquine, dolasetron, mesoridazine, moxifloxacin, pimozide, tacrolimus, pentamidine, thioridazine, ziprasidone. Increased risk of blood glucose disturbances w/ drugs that alter blood glucose concentrations (e.g. antidiabetics). Systemic admin may elevate plasma concentrations of theophylline, interfere caffeine metabolism, enhance effects of oral anticoagulant (warfarin and its derivatives), and transient elevations in serum creatinine w/ ciclosporin.

Pregnancy Category Note

Pregnancy: There are no available data in pregnant women to inform of a drug-associated risk Lactation: Excretion in milk unknown; consider the developmental and health benefits of breastfeeding along with the mother?s clinical need for therapy and any potential adverse effects on the breastfed child

Adult Dose

Ophthalmic Bacterial conjunctivitis Adult: As 0.3% soln: Instill 1 drop 2 hrly into affected eye(s) while awake (up to 8 times daily) for the 1st 2 days then reduce to 1 drop 4 times daily while awake for the next 5 days.

Child Dose

Ophthalmic Bacterial conjunctivitis Child: >1 yr: As 0.3% soln: Instill 1 drop 2 hrly into affected eye(s) while awake (up to 8 times daily) for the 1st 2 days then reduce to 1 drop 4 times daily while awake for the next 5 days.

Renal Dose

N/A

Administration

N/A

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.