May increase pigmentation of the iris, periorbital tissue and eyelashes. Active intraocular inflammation. Safety and efficacy have not been evaluated in the treatment of inflammatory, neovascular or angle closure glaucoma. Ensure at least an interval of 5 minutes between admin of ophthalmic preparations. Contact lenses should be removed prior to admin. Pregnancy, lactation.
Lactation: Excretion in milk unknown; use with caution
Indication
Open-angle glaucoma, Ocular hypertension
Contra Indication
Known hypersensitivity.
Dose
N/A
Side Effect
>10%
Conjunctival hyperemia (25-45%),Growth of eyelashes (15-45%),Ocular pruritus (15-45%)
1-10%
Ocular dryness (3-10%),Visual disturbance (3-10%),Ocular burning (3-10%),Foreign body sensation (3-10%),Ocular pain (3-10%),Pigmentation of the periocular skin (3-10%),Blepharitis (3-10%),Cataract (3-10%),Superficial punctate keratitis (3-10%),Eyelid erythema (3-10%),Ocular irritation (3-10%),Eyelash darkening (3-10%),Ocular discharge (1-3%),Tearing (1-3%),Photophobia (1-3%),Allergic conjunctivitis (1-3%),Asthenopia (1-3%),Increases in iris pigmentation (1-3%),Conjunctival edema (1-3%)
Frequency Not Defined
Periorbital erythema,Eye swelling,Eyelids: burning sensation, edema, irritation, pruritus,Iris hyperpigmentation,Lacrimation increased,Madarosis and trichorrhexis,Periorbital and lid changes associated with a deepening of the eyelid sulcus,Rash (including macular, erythematous, and pruritic limited to the eyelids and periorbital region),Skin discoloration (periorbital),Blurred vision
Pregnancy Category
Name :
C
Description
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks
Mode of Action
Bimatoprost is a prostamide analogue with ocular hypotensive action. It is postulated to lower intraocular pressure by increasing outflow of aqueous humor through both the trabecular meshwork and uveoscleral routes.
Interaction
N/A
Pregnancy Category Note
N/A
Adult Dose
Adult: Ophth Open-angle glaucoma; Ocular HTN As 0.03% soln: Instill 1 drop once nightly.
Child Dose
N/A
Renal Dose
N/A
Administration
N/A
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