Roxyzin - 25mg

Tablet

Pack Size : 10 Tablet x 1 Strip

Generics : Hydroxyzine Hydrochloride

Manufacturer : Incepta Pharmaceuticals Ltd.

Best Price * TK 20.00

* Delivery will be done in Dhaka city only.

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More Information About - Roxyzin - 25mg

Description

Generic Name

Hydroxyzine Hydrochloride

Precaution

Renal and hepatic impairment; narrow-angle glaucoma; epilepsy; prostatic hypertrophy; bladder neck obstruction; asthma; COPD. May impair ability to drive or operate machinery. Lactation: Excretion in milk unknown; use with caution

Indication

Pruritus, Allergic conditions, Generalized anxiety disorder, Psychoneurosis, Chronic urticaria, Atopic or contact dermatoses, Pre- or post-operative sedation

Contra Indication

Porphyria, neonates, pregnancy, lactation.

Dose

N/A

Side Effect

Dizziness, ataxia, fatigue, drowsiness, hallucination, seizure, dry mouth, nervousness, xerostomia, involuntary movements, slurred speech, headache, paraesthesia, tremor, blurred vision, resp depression, pruritus, rash, urticaria, allergic reaction.

Pregnancy Category

Name : Not Classified

Description

FDA has not yet classified the drug into a specified pregnancy category.

Mode of Action

Hydroxyzine, a piperazine derivative, blocks histamine H1-receptors on effector cells of the GI tract, blood vessels and resp tract. It is a sedating antihistamine w/ antimuscarinic and significant sedative properties. It also possesses skeletal muscle relaxing, bronchodilator, antiemetic and analgesic properties.

Interaction

Additive or may potentiate CNS depressant effects of opiates or other analgesics, barbiturates or other sedatives, and anaesth. MAOIs and TCAs potentiate antimuscarinic effects.

Pregnancy Category Note

Pregnancy category: Considered to be contraindicated in early (1st trimester) pregnancy until more human pregnancy data available; limited experience in human pregnancy, either for drug itself or drugs in same class or with similar mechanisms of action, including 1st trimester, current limited data suggests that the drug does not represent a significant risk of developmental toxicity including growth restriction, structural anomalies, functional/behavioral deficits, or death at any time in pregnancy Lactation: Excretion in milk unknown; use with caution

Adult Dose

Oral For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested: Adult: 50-100 mg 4 times daily. For use in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus: Adult: Initially, 25 mg at night increased if required up to 25 mg 3-4 times daily. As a sedative when used as a premedication and following general anesthesia: Adult: 50-100 mg. Hepatic impairment: Reduce total daily dose by 33%.

Child Dose

Oral For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested Children under 6 years: 50 mg daily in divided doses >6 years: 50 to 100 mg daily in divided doses. For use in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus Child: 6 mth to 6 yr Initially, 5-15 mg/day, increased to 50 mg/day in divided doses; >6 yr Initially, 15-25 mg/day, increased up to 50-100 mg/day in divided doses. As a sedative when used as a premedication and following general anesthesia Child: 0.6 mg/kg. Hepatic impairment: Reduce total daily dose by 33%. For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested,children under 6 years, 50 mg daily in divided doses and over 6 years, 50 to 100 mg daily in divided doses. For use in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus, children under 6 years, 50 mg daily in divided doses and over 6 years, 50 to 100 mg daily in divided doses. As a sedative when used as a premedication and following general anesthesia, 0.6 mg/kg in children.

Renal Dose

Renal Impairment >50 mL/min: Dose adjustment not necessary <50 mL/min: Administer 50% normal dose

Administration

May be taken with or without food.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.