FDA has not yet classified the drug into a specified pregnancy category.
Mode of Action
Erdosteine contains two sulfhydryl groups, which are freed after metabolic transformation in the liver. The liberated sulfhydryl groups break the disulphide bonds, which hold the glycoprotein fibres of mucus together. This makes the bronchial secretions more fluid and enhances elimination.
Interaction
N/A
Pregnancy Category Note
N/A
Adult Dose
Oral
As a mucolytic
Adult: 300 mg bid. Max duration: 10 days.
Hepatic Failure
Since there are no data in patients with severe liver failure, the use of erdosteine is not recommended in these patients.
Mild to Moderate Hepatic Failure
Dose should be reduced
Child Dose
N/A
Renal Dose
Since there are no data in patients with creatinine clearance <25ml/min, the use of erdosteine is not recommended in these patients.
Administration
The capsules must be swallowed whole with a glass of water.
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