More Information About - Fona Plus .1/2.5/100 gm Gel 10 gm
Description
Generic Name
Adapalene 0.1% + Benzoyl Peroxide 2.5%
Precaution
Exposure to sunlight, including sunlamps, should be minimized during the use of adapalene and benzoyle peroxide gel. Patients with high levels of sun exposure and those with inherent sensitivity to sun should exercise particular caution. Use of sunscreen products and protective apparel, (e.g., hat) are recommended when exposure cannot be avoided. Weather extremes, such as wind or cold, may be irritating to patients under treatment with adapalene and benzoyle peroxide gel.
Safety and effectiveness of Adapalene and Benzoyl peroxide gel in pediatric patients under the age of 9 years have not been established.
Indication
Acne
Contra Indication
Hypersensitive to any of the components.
Dose
N/A
Side Effect
>10%
Stinging/ burning (3-41%),Dryness (1-41%),Scaling (1-35%),Erythema (1-27%)
1-10%
Contact dermatitis (3%),Application site burning (2%),Application site irritation (1%),Skin irritation (1%)
Pregnancy Category
Name :
C
Description
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks
Mode of Action
Adapalene binds to specific retinoic acid nuclear receptors which normalises the differentiation of follicular epithelial cells resulting in decreased microcomedone formation.
Benzoyl peroxide has mild keratolytic effect and antimicrobial activity which is attributed to its oxidative property. It is active against S.epidermidis and P.acne.
Interaction
Adapalene: Increased irritation may occur with medicated or abrasive soaps, products with a pronounced drying effect and those containing alcohol or astringents.
Benzoyl Peroxide: PABA sunscreens may transiently discolour fabric.
Pregnancy Category Note
Pregnancy Category: C
Lactation: Unknown whether distributed in breast milk, exercise caution
Adult Dose
Apply a thin film of adapalene and benzoyle peroxide gel to affected areas of the face and/or trunk once daily after washing.
Use a pea-sized amount for each area of the face (e.g., forehead, chin, each cheek).
Avoid the eyes, lips and mucous membranes.
Child Dose
Child: >9 years: Apply thin film to affected facial areas and/or trunk qPM after washing
<9 years: Safety & efficacy has not been established.
Renal Dose
N/A
Administration
N/A
Disclaimer
The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.