Patients with sunburn, eczema. Pregnancy, lactation. Avoid excessive exposure to sunlight or UV irradiation. Keep away from the eyes, lips, nostrils and mucous membranes. Do not apply to cuts, abrasions, scaly or flaky skin, or patches of sunburned skin. Use with caution with preparations containing sulfur, resorcinol, or salicylic acid.
Indication
Acne
Contra Indication
Hypersensitivity.
Dose
N/A
Side Effect
Mild skin irritation, scaling, erythema, cutaneous dryness, sensations of stinging and burning, pruritus.
Pregnancy Category
Name :
C
Description
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks
Mode of Action
Adapalene binds to specific retinoic acid nuclear receptors which normalises the differentiation of follicular epithelial cells resulting in decreased microcomedone formation.
Interaction
Increased irritation may occur with medicated or abrasive soaps, products with a pronounced drying effect and those containing alcohol or astringents.
Pregnancy Category Note
Pregnancy category: C
Lactation: Excretion in milk unknown; use with caution
Adult Dose
Adult: Topical As 0.3% soln/cream/gel: Apply once daily at night.
Child Dose
N/A
Renal Dose
N/A
Administration
N/A
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