Cautions should be exercised if there is susceptibility to angle-closure glaucoma, urinary retention, severe liver impairment, mania and also in pregnancy and breast-feeding. Drowsiness may affect performance of skilled tasks (e.g. driving) so patient should be careful.
Lactation: may pass into breast milk; do not nurse
Patients with untreated narrow angle glaucoma or a tendency to urinary retention because doxepin HCl has an anticholinergic effect
Individuals who have shown previous sensitivity to any of its components
Dose
N/A
Side Effect
>10%
Burning/stinging (23%),Drowsiness (20%; esp if applied to >10% BSA)
1-10%
Dizziness,Dry mouth,Eczema exacerbated,Edema,Fatigue,Mental changes,Pruritus,Taste perversion
Pregnancy Category
Name :
B
Description
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.
Methylphenidate may increase plasma doxepin levels.
Potentially Fatal: Potentiates hypertensive action of sympathomimetics. Increased anticholinergic effects with MAOIs. Additive CNS effects with anticholinergics, CNS depressants and alcohol.
Pregnancy Category Note
Pregnancy Category: B
Lactation: May pass into breast milk; do not nurse
Adult Dose
Adult: apply thinly 3-4 times daily; usual max. 3 g per application; usual total max. 12 g daily; coverage should be less than 10% of body surface area.
Use in Elderly Patients:
Dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range.
Child Dose
Child over 12 years: apply thinly 3-4 times daily; usual max. 3 g per application; usual total max. 12 g daily; coverage should be less than 10% of body surface area.
The use of Doxepin cream in pediatric patients is not recommended.
Renal Dose
N/A
Administration
N/A
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