Cilosta 100mg

Tablet

Pack Size : 10 Tablet x 1 Strips

Generics : Cilostazol

Manufacturer : Square Pharmaceuticals Ltd.

Best Price * TK 120.90

* Delivery will be done in Dhaka city only.

Alternative Product

More Information About - Cilosta 100mg

Description

Generic Name

Cilostazol

Precaution

Congestive heart disease. Concurrent therapy with clopidogrel has not been studied for safety or efficacy. Pregnancy and lactation. Lactation: Excretion in milk unknown; not recommended

Indication

Peripheral vascular disease, Intermittent claudication

Contra Indication

Heart failure; known predisposition to bleeding; history of ventricular arrhythmias; QT interval prolongation; severe renal impairment; moderate to severe hepatic impairment.

Dose

N/A

Side Effect

>10% Headache (27-34%),Diarrhea (12-19%),Abnormal stools (12-15%),Infection (10-14%),Rhinitis (7-12%),Pharyngitis (7-10%) 1-10% Dizziness (9-10%),Palpitations (5-10%),Peripheral edema (7-9%),Back pain (6-7%),Dyspepsia (6%),Abdominal pain (4-5%),Tachycardia (4%),Increased cough (3-4%),Myalgia (2-3%),Atrial fibrillation (<2%),CHF (<2%),MI (<2%),Hematemesis (<2%),Ecchymosis (<2%),Blood in eye (<2%),Epistaxis (<2%),Hemoptysis (<2%),Nausea Frequency Not Defined Decreased platelet aggregation,Agranulocytosis,Aplastic anemia,Leukopenia,Thrombocytopenia,Stevens-Johnson syndrome

Pregnancy Category

Name : C

Description

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Mode of Action

Cilostazol is a reversible, selective inhibitor of phosphodiesterase-III (PDE-III), thereby suppressing cyclic adenosine monophosphate (cAMP) degradation. Increase in cAMP in platelets and blood vessels leads to inhibition of platelet aggregation and vasodilation. Cilostazol also inhibits adenosine uptake into cells, which augments the cAMP-elevating effect of PDE-III inhibition.

Interaction

Co-admin with drugs that affect CYP3A4 (erythromycin, other macrolides, diltiazem) or CYP2C19 (omeprazole) may influence the pharmacokinetics of cilostazol.

Pregnancy Category Note

Pregnancy category: C Lactation: Excretion in milk unknown; not recommended

Adult Dose

Oral Peripheral vascular disease Adult: 100 mg bid. May reduce dose in patients taking enzyme inhibitors concurrently. Hepatic Impairment Moderate to severe: Use caution

Child Dose

N/A

Renal Dose

Renal Impairment CrCl< 25 mL/min: Use caution

Administration

Should be taken on an empty stomach. Take at least ? hr before or 2 hr after meals.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.