Aphakic patient, pseudophakic patient w/ torn posterior lens capsule or anterior chamber lenses, or w/ known risk factor for cystoid macular oedema. Patient w/ history of intraocular inflammation (e.g. uveitis, iritis). Pregnancy and lactation. Patient Counselling Remove contact lenses prior to admin and reinsert after 15 min.
Lactation: distributed in milk in animals; caution if used in nursing women
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks
Mode of Action
Travoprost, a synthetic analogue of prostaglandin F2?, reduces intraocular pressure by increasing uveoscleral outflow of aqueous humour.
Interaction
Reduced therapeutic effect w/ NSAIDs.
Pregnancy Category Note
Pregnancy Category: C
Lactation: distributed in milk in animals; caution if used in nursing women
Adult Dose
Ophthalmic
Ocular hypertension; Open-angle glaucoma
Adult: As 0.004% soln: Instill 1 drop in the conjunctival sac of the affected eye(s) once daily, preferably in the evening.
Child Dose
Safety and efficacy not established
Renal Dose
N/A
Administration
N/A
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