Should be given cautiously to patients taking Levodopa as Pyridoxine reduces the effect of Levodopa.
Indication
Vitamin B deficiency. Glossitis, stomatitis, cheilosis, beriberi polyneuritis.
Contra Indication
Contraindicated in patients hypersensitive to any of its components.
Dose
N/A
Side Effect
Generally well tolerated.
Pregnancy Category
Name :
A
Description
Adequate and well-controlled human studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
Mode of Action
Vitamin B: Plays a role in the synthesis and maintenance of coenzyme A. Necessary for lipid metabolism, carbohydrate metabolism, tissue respiration, glycogenolysis, inhibition of very low-density lipoprotein (VLDL) synthesis. May increase chylomicron triglyceride removal from plasma.
Vitamin B12 (cyanocobalamin): Required for the maintenance of normal erythropoiesis, nucleoprotein and myelin synthesis, cell reproduction and normal growth; intrinsic factor, a glycoprotein secreted by the gastric mucosa, is required for active absorption of Vitamin B12 from the GI tract. Necessary for normal tissue respiration; plays a role in activation of pyridoxine and conversion of tryptophan to niacin.
Interaction
N/A
Pregnancy Category Note
N/A
Adult Dose
Oral
Adult:
Tablet/Capsule : 1-2 tab/cap, 3 times daily.
Syrup : 1-2 (5 ml spoonful) syrup three times a day.
Child Dose
Oral
Children: 1 (5 ml spoonful) syrup three times a day.
Infants: 1 (5 ml spoonful) syrup daily.
Renal Dose
N/A
Administration
N/A
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